With good rules (Stand on Soft 17, Double After Split, Late Surrender), the house edge is 0.32%. Generally speaking, the frequency and length of the dealer shuffle at a 6-deck table results in about 100 hands per hour (assuming four players, on average, at the table).
Since, even with perfect basic strategy, you will lose money with each hand you play, the biggest difference will be the speed with which your bankroll shrinks. Obsessed, I'm not a card counter but I can't stand the continuous shuffle machines(CSM).
